Jealousy, loyalty, and a family feud between two brothers are all at play in the House of the Seven Gables, based on the classic novel by Nathaniel Hawthorne. The sudden death of Jaffrey (George Sanders) and Clifford (Vincent Price) Puncheons father provides the vengeful and vindictive Jaffrey with the perfect opportunity to get his brother out of the way and seize the family fortune. Framed for murder and forced to leave his Fiancée (Margaret Lindsay) behind, Clifford is sent off to prison, where he befriends Matthew Hargrave (Dick Foran), the descendent of the Maule family, with whom the Puncheons have a long history of turbulence. Can the two join together to foil Jaffrey, or are the families destined to repeat the mistakes of the past and live out the curse of their ancestors?